Hyperhomocysteinemia is a rare condition which predisposes to arterial and venous thrombosis.Plasma homocysteine levels are influenced by many genetic factors and environmental factors.Increased levels of homocysteine at high-altitude Vacuum Extension Pipe areas (HAA) can predispose to upper-extremity deep-vein thrombosis Cushioned lunge rein (UEDVT).Therefore, awareness by the medical authorities regarding this entity at HAA as a sole cause of UEDVT needs to be established.
Prompt reduction in the homocysteine level can be therapeutic as well as prophylactic in preventing the morbidity.